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Melatonin: Dose, Timing & Jet Lag

Lying awake after a late shift, or landing in Bahrain after a long-haul flight? Melatonin is one of the few sleep-related supplements with authorised EU claims, and the amounts behind them are small. This guide covers doses, timing, forms, children and medicine interactions.

By the Healthana Editorial Team · Last reviewed: 01 Nov 2026

Daily reference intake (NRV)No NRV set
Upper limit for adultsNo EFSA upper limit set; national rules vary (see guidance below)

What melatonin is

Melatonin is a hormone made by the pineal gland in the brain. Levels rise in the evening as it gets dark and fall in the morning, which is why it is often called the darkness hormone and linked with the body clock. Light at night, shift work and crossing time zones all affect when melatonin is released.

Supplements contain melatonin made in a laboratory, identical to the body's own. Two health claims are authorised in the EU, each with specific conditions, and you will find them in the authorised claims below. Melatonin products sit in our sleep care range.

Forms you'll see on labels

FormWhat to know
Standard (immediate-release) tabletsRelease melatonin quickly. Commonly 1 mg to 5 mg.
Prolonged-release tabletsRelease melatonin gradually overnight. In the UK, the 2 mg prolonged-release form is a prescription medicine.
Fast-dissolve tablets and oral filmsDissolve on or under the tongue, no water needed.
GummiesPopular and easy to take, but a 2023 US study found most melatonin gummies did not match the amount on the label.
Sprays and dropsAllow small, adjustable amounts. Check how much melatonin each spray or drop provides.
Combination formulasMelatonin with magnesium, L-theanine, chamomile, valerian or vitamin B6. Check the melatonin amount separately.

How much: the amounts behind the claims

  • NRV: none. Melatonin is not a nutrient.
  • Claim conditions: the EU claim about falling asleep applies to 1 mg taken close to bedtime. The jet lag claim applies to at least 0.5 mg taken close to bedtime on the first day of travel and the first few days after arrival.
  • Products on shelves: range from 1 mg to 10 mg or more. Higher amounts are not needed to meet the claim conditions.
  • Upper limit: EFSA has not set one. Rules differ by country: several European countries cap the amount allowed in supplements, while others, including the UK, regulate melatonin as a medicine.
  • Duration: short-term use appears safe for most adults, but long-term safety data are limited.
  • Food sources: tiny amounts occur in foods such as tart cherries, but not at supplement levels.

Who should check with a doctor or pharmacist first

  • Children and teenagers: some products are labelled for children, but dosing and long-term effects in children are not well established. Check the age on the pack and ask a doctor or pharmacist before use. Store gummies out of children's reach: accidental swallowing by young children has risen sharply.
  • Pregnancy and breastfeeding: research is limited, so ask your doctor first.
  • Medicines: people with epilepsy and people taking blood thinners such as warfarin need medical advice. The antidepressant fluvoxamine can greatly raise melatonin levels. Sedatives and sleeping tablets can add to drowsiness.
  • Autoimmune conditions such as rheumatoid arthritis, multiple sclerosis or lupus, and liver or kidney problems.
  • Older adults: may clear melatonin more slowly, which can cause next-day drowsiness.
  • Driving and alcohol: do not drive or operate machinery if you feel drowsy, and avoid alcohol with melatonin.

How to read the label

  1. Amount per serving: check whether the serving is one or two gummies or tablets. 2 gummies at 2.5 mg each is 5 mg.
  2. Compare with the claim conditions: 1 mg for falling asleep, at least 0.5 mg for jet lag.
  3. Release type: immediate-release and prolonged-release products are used differently.
  4. Other actives: combination products may include botanicals such as valerian or passionflower; check each ingredient if you take medicines.
  5. Age guidance: look for the stated age range and any warnings about children.

Bahrain and GCC notes

Long-haul flights between the Gulf and Europe, Asia or the Americas make jet lag a common reason to consider melatonin; follow the claim timing above. During Ramadan, sleep is often split around suhoor, so take melatonin only close to the time you intend to sleep and ask a pharmacist if your routine changes. Keep gummies and fast-dissolve tablets away from heat and humidity, and close packs tightly.

Nerhadou Melacryst Melatonin 3 mg, 20 Oral Dissolving Films
Label check

Reading a real label

Nerhadou Melacryst Melatonin 3 mg, 20 Oral Dissolving Films
On the labelWhat it means
3 mg melatonin per filmMelts on the tongue, no water needed
1 mg close to bedtimeThe amount the authorised sleep claim is based on
Adults onlyAs stated on the pack
20 films20 nights
Figures from the product's own label. Always check the pack in your hand.See this product
EU-authorised health claims
  • Melatonin contributes to the reduction of time taken to fall asleep
  • Melatonin contributes to the alleviation of subjective feelings of jet lag

Sleep onset: 1 mg taken close to bedtime. Jet lag: at least 0.5 mg taken close to bedtime on the first day of travel and the first few days after arrival.

Frequently asked questions

How much melatonin do the EU claims refer to?

The claim about falling asleep applies to 1 mg taken close to bedtime. The jet lag claim applies to at least 0.5 mg close to bedtime on the first day of travel and the first few days after arrival.

Is a 10 mg tablet better than 1 mg?

Not necessarily. The authorised claims are based on 1 mg and 0.5 mg, and higher amounts can raise the chance of next-day drowsiness.

Can children take melatonin?

Some products are labelled for children, but dosing and long-term effects are not well established. Check the age on the pack and ask a doctor or pharmacist first.

Can I take melatonin with other medicines?

Ask a pharmacist first, especially if you take blood thinners, epilepsy medicines, sedatives or the antidepressant fluvoxamine.

This page is general information from Healthana, not medical advice. Food supplements should not replace a varied, balanced diet and a healthy lifestyle. Speak to your doctor or pharmacist if you are pregnant or breastfeeding, take medication or have a medical condition. Editorial policy
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